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???msg.participant.card.lastName.label??? : Fontaine
???msg.participant.card.firstName.label??? : Judith
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- DIVESEA DINARD
- (Stagiaire, Centre National de la Recherche Scientifique)
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Kourany-Lefoll E., Païs M., Sévenet T., Guillet E., Montagnac A., Fontaine C., Guénard D., Adeline M.T. & Debitus C. 1992. Phloeodictines A and B: New antibacterial and cytotoxic Bicyclic Amidinium Salts from the New Caledonian Sponge, Phleodictyon sp. Journal of Organic Chemistry 57(14): 3832-3835
???msg.biblio.abstract.label??? [+] [-]Two new alkaloids, phloeodictine A (1) and phloeodictine B (21, possessing an unprecedented 6-hydroxy- 1,2,3,4 tetrahydropyrrolo[ 1,2-a]pyrimidinium skeleton have been isolated from an undescribed species of the deep sponge Phbeodictyon. The structures were determined by extensive spectroscopic analysis particularly two-dimensional NMR experiments. Both compounds exhibited in vitzo antibacterial activity against Gram-positive and Gram-negative bacteria and were moderately cytotoxic against KB cells.
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Païs M., Fontaine C., Laurent D., La Barre S. & Guittet E. 1987. Stylotelline, a New Sesquiterpene Isocyanide from the Sponge Stylotella Sp. Application of Zd-Nmr in Structure Determination. Tetrahedron letters 28(13): 1409-1412
???msg.biblio.abstract.label??? [+] [-]The sesquiterpene isocyanide stylotelline isolated from the marine sponge Stylotella sp. was asigned the structure 1a (absolute stereochemietry) on the basis of spectral - essentially 2D-NMR - and chemical data.
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